Gene variant reduces cholesterol by two mechanisms
High levels of low-density lipoprotein (LDL) cholesterol increases the risk for coronary heart disease.
Jul 2, 2012
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High levels of low-density lipoprotein (LDL) cholesterol increases the risk for coronary heart disease.
Jul 2, 2012
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When it comes to thinking about lipids and heart health, cholesterol often comes to mind. Along with age, blood pressure, and underlying conditions, cholesterol—a fat that circulates in the bloodstream—is one of many ...
Jul 26, 2023
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(HealthDay)—At lower values of measured low-density lipoprotein cholesterol (LDL-C), the variation and bias of calculated LDL-C increases, according to a study published in the Aug. 15 issue of The American Journal of Cardiology.
Aug 11, 2015
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Fasting prior to blood lipid tests appears to have limited association with lipid subclass levels, suggesting that fasting for routine lipid level determinations may be unnecessary, according to a report published Online ...
Nov 12, 2012
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(HealthDay)—Plasma levels of proprotein convertase subtilisin/kexin type 9 (PCSK9) may help assess apparent resistance to PCSK9 inhibitors, according to a research letter published online Nov. 28 in the Annals of Internal ...
Nov 29, 2017
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Scientists from UCLA and the Howard Hughes Medical Institute successfully used a gene that suppresses cholesterol levels as part of a treatment to reduce plaque in mice with a disorder called familial hypercholesterolemia. ...
Aug 28, 2017
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An analysis using genetics finds that increased low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), and possibly triglyceride (TG) levels are associated with a lower risk of diabetes, ...
Aug 3, 2016
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A major Cardiovascular (CV) risk factor is low-density Lipoprotein Cholesterol (LDL-C). A lot of evidence that was accumulated supports a linear association between LDL-C levels and CV risk. However, whether the lower limit ...
Jan 2, 2019
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Stopping statin treatment early could substantially reduce lifetime protection against heart disease since a large share of the benefit occurs later in life. That's the finding of a modeling study presented at ESC Congress ...
Aug 25, 2022
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(HealthDay)—The glucagon receptor blocker REGN1193, a fully human monoclonal antibody, seems safe and tolerable enough for further development, according to a study published online July 28 in Diabetes, Obesity and Metabolism.
Aug 4, 2017
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