Medical research

Triglycerides: A new frontier in detecting and treating disease

When it comes to thinking about lipids and heart health, cholesterol often comes to mind. Along with age, blood pressure, and underlying conditions, cholesterol—a fat that circulates in the bloodstream—is one of many ...

Cardiology

Calculated LDL-C varies at lower values of measured LDL-C

(HealthDay)—At lower values of measured low-density lipoprotein cholesterol (LDL-C), the variation and bias of calculated LDL-C increases, according to a study published in the Aug. 15 issue of The American Journal of Cardiology.

Cardiology

Measuring plasma PCSK9 may ID resistance to PCSK9 inhibitors

(HealthDay)—Plasma levels of proprotein convertase subtilisin/kexin type 9 (PCSK9) may help assess apparent resistance to PCSK9 inhibitors, according to a research letter published online Nov. 28 in the Annals of Internal ...

Cardiology

Gene therapy using 'junk DNA' could lower risk for heart disease

Scientists from UCLA and the Howard Hughes Medical Institute successfully used a gene that suppresses cholesterol levels as part of a treatment to reduce plaque in mice with a disorder called familial hypercholesterolemia. ...

Cardiology

Is very low LDL-C harmful?

A major Cardiovascular (CV) risk factor is low-density Lipoprotein Cholesterol (LDL-C). A lot of evidence that was accumulated supports a linear association between LDL-C levels and CV risk. However, whether the lower limit ...

Cardiology

Study highlights lifelong benefits of statin therapy

Stopping statin treatment early could substantially reduce lifetime protection against heart disease since a large share of the benefit occurs later in life. That's the finding of a modeling study presented at ESC Congress ...

Diabetes

mAb glucagon receptor blocker suitable for further development

(HealthDay)—The glucagon receptor blocker REGN1193, a fully human monoclonal antibody, seems safe and tolerable enough for further development, according to a study published online July 28 in Diabetes, Obesity and Metabolism.

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