Diseases, Conditions, Syndromes

Researchers identify new therapeutic target for pulmonary fibrosis

Researchers in Japan have identified a genetic mutation that causes a severe lung disease called idiopathic pulmonary fibrosis (IPF) by killing the cells lining the lung's airways. The study, which will be published October ...

Diseases, Conditions, Syndromes

Nintedanib slows progression for broad range of scarring lung diseases

Nintedanib, a medication approved for the treatment of idiopathic pulmonary fibrosis, slows the decline in lung function among patients with a broad range of scarring lung diseases. The findings, published in the New England ...

Diseases, Conditions, Syndromes

Promising steps towards a treatment for pulmonary fibrosis

Idiopathic pulmonary fibrosis (IPF) is a type of lung disease that results in scarring of the lungs, also known as fibrosis. Over time, the fibrosis gets increasingly worse so that it becomes hard for those with the condition ...

Medical research

In cystic fibrosis, lungs feed deadly bacteria

In cystic fibrosis, Pseudomonas aeruginosa is a much-feared pathogen. The bacterium easily colonizes the lungs of people with cystic fibrosis, leading to chronic infections that are almost impossible to eradicate and are ...

Diseases, Conditions, Syndromes

Ivacaftor may reduce common infections in patients with CF

Patients with cystic fibrosis who take ivacaftor appear to have fewer respiratory infections over time than those not taking the drug, according to new research published online in the Annals of the American Thoracic Society.

Diseases, Conditions, Syndromes

Shaky scaffold changes lung infrastructure

Our lungs work tirelessly all through the day to keep us breathing, seamlessly expanding and contracting. When lung tissue becomes damaged and scarred, it can lose its flexibility, making it harder to breathe.

Medical research

A new target for the treatment of idiopathic pulmonary fibrosis

An article published in Experimental Biology and Medicine identifies a new target for the treatment of idiopathic pulmonary fibrosis. The study, led by Dr. Huaping Dai in the Department of Pulmonary and Critical Care Medicine ...

Diseases, Conditions, Syndromes

Adding clinical variables improves accuracy of lung allocation score

Implemented back in 2005, the lung allocation score is used to prioritize patients awaiting lung transplants in the United States. Sicker transplant candidates have a higher calculated score and are placed at the top of the ...

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