Medical research

Oxygen therapy harms lung microbiome in mice

One of the hallmarks of severe COVID-19 is shortness of breath and significantly reduced levels of oxygen in the blood, called hypoxemia. Upon hospitalization, these patients are administered oxygen in an attempt to bring ...

Diseases, Conditions, Syndromes

Lung microbiome may help predict outcomes in critically ill patients

Changes in the lung microbiome may help predict how well critically ill patients will respond to care, according to new research published online in the American Thoracic Society's American Journal of Respiratory and Critical ...

Immunology

Human fetal lungs harbor a microbiome signature

The lungs and placentas of fetuses in the womb—as young as 11 weeks after conception—already show a bacterial microbiome signature, which suggests that bacteria may colonize the lungs well before birth. This first-time ...

Diseases, Conditions, Syndromes

Obesity, heart disease, and diabetes may be communicable

Non-communicable diseases including heart disease, cancer and lung disease are now the most common causes of death, accounting for 70 percent of deaths worldwide. These diseases are considered "non-communicable" because they ...

Obstetrics & gynaecology

Maternal antibiotic treatment may harm preemies' lungs

New research in mice suggests that exposure to antibiotics before birth may impair lung development in premature infants. The study, the first to explore the gut-lung axis in prematurity, is published ahead of print in the ...

Diseases, Conditions, Syndromes

Pioneering microbiome findings shed light on aspiration

When children have respiratory infections, clinicians tend to blame gastroesophageal reflux, based on the assumption that bacteria-laden stomach contents rise into the mouth and are then aspirated. As a result, clinicians ...

Immunology

Fungus from the intestinal mucosa can affect lung health

Writing in the journal Cell, a research team from Cologne and Kiel describes the mechanism of immune cross-reactivity. The immune system's reaction to Candida albicans in the intestine seems to amplify pathogenic immune processes ...

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