Arthritis & Rheumatism

Adverse childhood experiences negatively impact adults with lupus

Adults with lupus who report having had adverse childhood experiences (ACEs), such as abuse, neglect and household challenges, report higher disease activity, depression and poorer overall health compared to those without ...

Diseases, Conditions, Syndromes

Study links patrolling monocytes to lupus-related kidney disease

A study led by St. Jude Children's Research Hospital has found evidence suggesting that patrolling monocytes may drive glomerulonephritis, inflammation of the kidneys, in patients with lupus. The findings overturn the previously ...

Immunology

Altered gut microbiome seen in patients with active lupus

(HealthDay)—The microbiome of patients with systemic lupus erythematosus (SLE), particularly those with increased disease activity, has reduced taxonomic complexity, according to a study published online Feb. 19 in the ...

Immunology

Lupus strongly linked to imbalances in gut microbiome

The disease systemic lupus erythematosus (SLE)—marked by the attack on joints, skin, and kidneys by the body's immune system—is linked to an abnormal mix of bacteria in the gut. This is according to a new study led by ...

Arthritis & Rheumatism

Researchers reveal how receptor TLR-9 protects against lupus

When the pathogen-sensing intracellular receptors TLR-7 and TLR-9 were implicated in systemic lupus erythematosus (SLE), it was suspected that their removal would lessen the severity of the disease. However, while this held ...

Genetics

How a single faulty gene can lead to lupus

A research team at the Academy of Immunology and Microbiology, within the Institute for Basic Science (IBS) & Pohang University of Science and Technology (POSTECH) in South Korea has discovered the role of a key gene involved ...

Arthritis & Rheumatism

Study shows volunteering benefits those with lupus

Conventional wisdom has it that volunteering is good for you, and a study at Hospital for Special Surgery (HSS) shows that to be true for people with lupus volunteering in a peer support and education program.

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