Immunology

TB dogma upended: Even uninfected cells trigger immune defenses

Experimenting with mice, infectious disease experts at NYU Langone Medical Center have found that immune system cells uninfected with the bacterium that causes tuberculosis trigger immune system T cells to fight the disease. ...

Oncology & Cancer

Arming the immune system to fight cancer

In 2004, a form of cancer known as neuroblastoma claimed the life of Alexandra (Alex) Scott, a little girl who gained national attention for using her lemonade stand to raise money for cancer research. Now, the organization ...

Medical research

New function for a messenger molecule

ETH Zurich Assistant Professor Cornelia Halin and her colleagues have discovered a new function of the well-known messenger protein interleukin-7: it facilitates the drainage of lymph fluid from tissues. In the future, the ...

Immunology

Lymph nodes with location memory

Regulatory T cells (or "Tregs" for short) play a central role in the human immune system: They guide all of the other immune cells and make sure they are tolerant of the body's own cells and harmless foreign substances. How ...

Surgery

Nonsentinel lymph nodes key factor in melanoma prognosis

(HealthDay)—Nonsentinel lymph node (NSLN) positivity is a significant prognostic factor in patients with stage III melanoma, associated with shorter overall and disease-specific survival, according to research published ...

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