Oncology & Cancer

Cancer stem cell vaccine in development shows antitumor effect

Scientists may have discovered a new paradigm for immunotherapy against cancer by priming antibodies and T cells with cancer stem cells, according to a study published in Cancer Research, a journal of the American Association ...

Immunology

From sleeping cell to assassin—how immune cells work

Scientists at the University of Dundee have carried out one of the most comprehensive studies into how immune cells sense and respond to their environment to fight infection and destroy tumours.

Immunology

Understanding the origins and function of CD14+ immune cells

Dendritic cells and macrophages are immune cells that orchestrate diverse immune functions within many body tissues, including the skin. New work by A*STAR researchers and colleagues shows that CD14+ cells in the skin—long ...

Oncology & Cancer

Cancer: The immune system attacks tumors remotely

How does the immune system act to limit tumor development? Using in vivo imaging tools, scientists from the Institut Pasteur and Inserm described the spatiotemporal activity of tumor-infiltrating T lymphocytes, both locally ...

Oncology & Cancer

Mutation's role in blood cancers revealed by ideal team-up

A genetic mutation that disrupts how DNA sends messages to the rest of a cell has been linked to a large number of blood cancers. Thanks to a collaboration between biologists at Cold Spring Harbor Laboratory (CSHL) and an ...

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