Immunology

Study finds how to shutdown cancer's powerful master protein

The powerful master regulatory transcription factor called Bcl6 is key to the survival of a majority of aggressive lymphomas, which arise from the B-cells of the immune system. The protein has long been considered too complex ...

Oncology & Cancer

Cellular fuel gauge may hold the key to restricting cancer growth

Researchers at McGill University have discovered that a key regulator of energy metabolism in cancer cells known as the AMP-activated protein kinase (AMPK) may play a crucial role in restricting cancer cell growth. AMPK acts ...

Genetics

Genome sequencing of Burkitt Lymphoma reveals unique mutation

In the first broad genetic landscape mapped of a Burkitt lymphoma tumor, scientists at Duke Medicine and their collaborators identified 70 mutations, including several that had not previously been associated with cancer and ...

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