Although Parkinson's disease has been recognized for more than 100 years, no treatments can slow or halt the disease's progress, let alone cure it. One of the major factors underlying this lack of progress is our relatively ...
Apr 2, 2024
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Researchers in South Australia have found a genetic link between Alzheimer's disease and the endo-lysosomal system, a critical part of biological recycling machinery that maintains the health of brain cells.
Aug 21, 2018
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The role played by mutations in the LRRK2 gene in promoting Parkinson's disease has long intrigued scientists, and even led to an experimental drug that inhibits the over-active protein. Yet exactly how LRRK2 triggers this ...
Jul 26, 2023
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For long-distance transportation within the cell, RNA molecules rely on hitchhiking.
Sep 19, 2019
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Over the last few decades, neurodegenerative diseases became one of the top 10 global causes of death. Researchers worldwide are making a strong effort to understand neurodegenerative diseases pathogenesis, which is essential ...
Jul 22, 2021
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Researchers have identified a bacterial protein that triggers a self-inflicted cell death pathway in immune system cells and could lead to a better understanding of an important cellular structure.
Mar 17, 2015
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A new therapeutic approach may one day delay neurodegeneration typical of a disease called mucopolysaccharidoses IIIB (MPS IIIB). Neurodegeneration in this condition results from the abnormal accumulation of essential cellular ...
Jun 20, 2018
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A mutated protein expressed in lysosomes may contribute to Parkinson's disease, according to a new Northwestern Medicine study published in the Journal of Cell Biology.
Mar 12, 2024
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A mutation in the CLCN6 gene is associated with a novel, particularly severe neurodegenerative disorder. Scientists from the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) and the Max Delbrück Center für ...
Nov 19, 2020
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New Peter Mac research recently published in Proceedings of the National Academy of Sciences (PNAS) has discovered a fundamental breakthrough related to the development of liver cancer.
Jun 1, 2023
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