Oncology & Cancer

Understanding the mechanism behind melanoma resistance to treatment

In many cases of malignant melanoma, the effect of targeted treatment is lost over time. A research team from UZH and USZ has now discovered that a factor secreted by tumor cells is responsible for the resistance. These findings ...

Oncology & Cancer

Multicancer early detection tests for cancer diagnosis

Cancer remains one of the most formidable public health challenges, causing significant mortality globally. In 2022 alone, there were approximately 19.3 million new cancer diagnoses and 10 million cancer-related deaths worldwide. ...

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Malignancy

Malignancy (from the Latin roots mal- = "bad" and -genus = "born") is the tendency of a medical condition, especially tumors to become progressively worse and to potentially result in death. It is characterized by the properties of anaplasia, invasiveness, and metastasis. Malignant is a corresponding adjectival medical term used to describe a severe and progressively worsening disease. The term is most familiar as a description of cancer. A malignant tumor may be contrasted with a non-cancerous benign tumor in that a malignancy is not self-limited in its growth, is capable of invading into adjacent tissues, and may be capable of spreading to distant tissues (metastasizing), while a benign tumor has none of those properties. Malignant tumor is synonymous with cancer. Uses of "malignant" in oncology:

Non-oncologic disorders referred to as "malignant":

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