Oncology & Cancer

A hijacking of healthy cellular circuits

Proteins that control cell growth are often mutated in cancer, and their aberrant signaling drives the wild proliferation of cells that gives rise to tumors. One such protein, the epidermal growth factor receptor (EGFR), ...

Oncology & Cancer

KDM1 may represent a new therapeutic target for glioma

Researchers have generated preclinical data demonstrating that the protein KDM1, which functions as a lysine demethylase, is a potential target for glioma treatment, according to Gangadhara R. Sareddy, Ph.D., a postdoctoral ...

Oncology & Cancer

Immortality gene mutation identifies brain tumors, other cancers

Newly identified mutations in a gene that makes cells immortal appear to play a pivotal role in three of the most common types of brain tumors, as well as cancers of the liver, tongue and urinary tract, according to research ...

Oncology & Cancer

Corticorelin acetate has steroid-sparing effect in brain cancer

(HealthDay)—Corticorelin acetate (CrA) administration to patients with peritumoral brain edema (PBE) allows the reduction of steroid doses and is associated with reduced incidence and severity of steroid-induced myopathy ...

Oncology & Cancer

Researchers identify enzyme involved in deadly brain tumors

One of the most common types of brain tumors in adults, glioblastoma multiforme, is one of the most devastating. Even with recent advances in surgery, radiation and chemotherapy, the aggressive and invasive tumors become ...

Oncology & Cancer

New biomarker may help in detecting gliomas

Researchers using sophisticated genetic testing techniques have identified a promising new biomarker for diagnosis of glioma—the most common type of malignant brain tumor, reports the January issue of Neurosurgery, official ...

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