(Medical Xpress) -- Doctors at Washington University School of Medicine in St. Louis have shown that a new drug makes chemotherapy more effective in treating acute myeloid leukemia, a cancer of the white blood cells. Instead ...
Mar 20, 2012
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Chemotherapy is one of the most important treatments for all types of cancer. It involves the use of drugs that kill abnormally multiplying cells. The therapy uses one or more drugs in combination and has been practised since ...
Jun 27, 2014
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Thanks to the 'cut and paste' gene editing technique CRISPR, scientists are homing in on a cure for sickle cell disease—a genetic blood disorder—while other research is looking at how to expand the potential of CRISPR-based ...
Dec 16, 2019
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Scientists at the Children's Medical Center Research Institute at UT Southwestern (CRI) have determined how the body responds during times of emergency when it needs more blood cells. In a study published in Nature, researchers ...
Nov 16, 2015
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As a child, Lynn Aureli didn't know that a particular genetic change contributed to her acute myeloid leukemia (AML)—an alteration that eventually would help explain the cancer's lack of response to chemotherapy. Nor was ...
Jan 27, 2023
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Half-matched bone marrow or stem cell transplants for blood cancer patients have typically been associated with disappointing clinical outcomes. However, a clinical trial conducted at the Kimmel Cancer Center at Jefferson ...
Sep 1, 2011
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Heart failure is a leading cause of death in Canada. As part of the ongoing IMPACT-CABG clinical trial to treat advanced heart failure, physicians at the Peter Munk Cardiac Centre performed the first cardiac stem cell transplant ...
Jan 26, 2012
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University Hospitals (UH) Case Medical Center, Case Western Reserve University School of Medicine and Lentigen Corporation announced today the initiation of a novel Phase I clinical trial of LG631 gene therapy for the protection ...
Nov 14, 2011
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One major challenge in cancer research is developing robust pre-clinical models for new therapies, ones that will accurately reflect a human response to a novel compound. All too often, a potential treatment that initially ...
Oct 5, 2017
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In mice, inflammation in early to mid-life leads to a permanent decline in functional blood stem cells, according to a recent publication by scientists from the German Cancer Research Center (DKFZ) and the Stem Cell Institute ...
Aug 4, 2022
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