Chemotherapy has a damaging effect on hematopoietic stem and progenitor cells (HSPCs) in bone marrow. However, once chemotherapy ends, HSPCs regenerate, a process that has remained unknown—until now. In a new study, researchers ...
Mar 5, 2021
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A team of researchers led by Tatsuo Kawai of Massachusetts General Hospital, Department of Surgery, Harvard Medical School, Boston, has found a less-intensive way to promote bone marrow transfusion success. In their paper, ...
Malaysian scientists have provided evidence that a widely used chemical is more toxic to certain blood cell precursors in the bone marrow than to others.
Jun 24, 2016
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UCLA researchers have developed a stem cell gene therapy cure for babies born with adenosine deaminase-deficient severe combined immunodeficiency, a rare and life-threatening condition that can be fatal within the first year ...
Mar 28, 2017
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In preclinical trials, Stanford scientists and their collaborators harnessed the gene-editing system CRISPR-Cas9 to replace the mutated gene underpinning the devastating immune disease.
Apr 11, 2019
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Scientists in Manchester, who have developed a stem cell gene therapy to reverse a fatal childhood illness, have agreed to work with a new therapeutics company to test it in a human trial.
May 11, 2016
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Cell therapy may present an option for patients with ischemic heart disease to use their own bone marrow cells to repair the damaged areas of their hearts, and may pave the way for future treatment options, according to the ...
Mar 24, 2012
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Using a technique that avoids the use of high-dose chemotherapy and radiation in preparation for a stem cell transplant, physicians at the University of Illinois Hospital & Health Sciences System have documented the first ...
Mar 20, 2017
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Hematopoietic stem cells from a healthy donor can help patients suffering from acute leukemia. However, the side effects of therapies are often severe. A group of researchers led by the University of Zurich have now shown ...
May 8, 2020
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New animal research is helping explain why at least five people have become HIV-free after receiving a stem cell transplant. The study's insights may bring scientists closer to developing what they hope will become a widespread ...
May 25, 2023
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