Medical research

HDAC3 role in B-cell development

Histone deacetylases (HDACs) are enzymes that modulate gene expression and have important roles in development and disease. HDAC inhibitors are active against lymphoma, and understanding the roles of specific HDACs is important ...

Medical research

Bone disease traced to the Middle Ages

The special form of the bone disease osteopetrosis that exists in Västerbotten is due to a gene mutation that can be traced back to the Middle Ages and leads to defective bone resorption, according to new research led at ...

Surgery

New strategies for donor kidney preservation

New treatment strategies over the last few decades have meant that nowadays 95 percent of transplanted kidneys function well for at least one year and that the average lifespan of a transplanted organ is between 10 and 15 ...

Medical research

New finding affecting immune reconstitution related to B cells

Researchers from the Children's Center for Cancer and Blood Diseases at Children's Hospital Los Angeles examined the mechanisms of B cell immune reconstitution in pediatric patients who had undergone bone marrow transplantation ...

Medical research

Engineered bone marrow could make transplants safer

Engineers at the University of California San Diego have developed biomimetic bone tissues that could one day provide new bone marrow for patients needing transplants.

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