Imiquimod, a drug used to treat skin cancer, has been shown to have a previously unknown effect on immune cells. The drug transforms cells known as dendritic cells into "tumour killers" that attack the tumour directly and ...
Mar 26, 2012
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In a Phase 1 trial, patients with an advanced or aggressive form of systemic mastocytosis (AdvSM), a rare blood disorder, had rapid and durable responses with few adverse effects following treatment with an investigational ...
Dec 10, 2017
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(Medical Xpress) -- Allergies, or hypersensitivities of the immune system, are more common than ever before. According to the Asthma and Allergies Foundation of America, one in five Americans suffers from an allergy — ...
Aug 2, 2012
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Allergies are the commonest cause of asthma. The immune system over-reacts to harmless substances such as birch or grass pollen, for example, forming immunoglobulin E antibodies (IgE). Together with the inflammatory cells ...
Mar 3, 2017
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Is there anything more exciting than a battle of the sexes? In popular culture, this usually focuses on societal gender roles. But, there's another battle of the sexes, a biological war waged by the body's immune system. ...
Feb 14, 2019
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Researchers at National Jewish Health have discovered a novel target for the treatment of food allergies. Erwin Gelfand, MD, and his colleagues report in the October 2012 issue of the Journal of Allergy and Clinical Immunology ...
Nov 1, 2012
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Eosinophilic gastritis and duodenitis are inflammatory diseases characterized by high levels of eosinophils and mast cells (immune system cells) in the stomach and duodenum. These disorders are often underdiagnosed and symptoms ...
Oct 22, 2020
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Targeted, successful cancer treatments are very often accompanied by unpleasant side effects. Especially in anti-EGFR treatments the skin is often so badly affected by inflammations that patients consider breaking off the ...
Aug 22, 2013
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A study led by University of Cincinnati (UC) lipid metabolism researchers lends additional insight into how bacteria in the gut, or lack thereof, influences intestinal mast cells (MMC) activation and perhaps fat absorption. ...
Sep 8, 2016
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Although allergies are widespread, their diagnosis is complex and, depending on the type of allergy, the prospects of success with therapy are not always clear. Skin tests so far have been unpleasant, time-consuming and associated ...
Mar 21, 2022
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