Medical research

Receptors under flow: Mechanosensitive GPCRs

An LMU team has clarified how a receptor which is involved in the regulation of vital physiological processes senses the mechanical forces that act on blood vessels. The findings could suggest new therapies for diseases of ...

Psychology & Psychiatry

Study sheds light on link between cannabis, anxiety and stress

A molecule produced by the brain that activates the same receptors as marijuana is protective against stress by reducing anxiety-causing connections between two brain regions, Vanderbilt University Medical Center researchers ...

Oncology & Cancer

Compound may play role in halting panceatic cancer

In early test tube and mouse studies, investigators at Johns Hopkins Medicine and the Johns Hopkins Kimmel Cancer Center have found that nonmuscle myosin IIC (MYH14), a protein activated in response to mechanical stress, ...

Medications

Stress hormones promote breast cancer metastasis

It has long been thought that stress contributes to cancer progression. Scientists from the University of Basel and the University Hospital of Basel have deciphered the molecular mechanisms linking breast cancer metastasis ...

Neuroscience

Intervening in glial cells protects neurons in Parkinson's model

Loss of dopaminergic neurons is a hallmark of Parkinson's disease pathology. When dopaminergic neurons are stressed, they send out a call for help to nearby glial cells that are tasked with providing neuronal support, protection ...

Medical research

Blocking toxic-protein production in ALS

Patients with ALS frequently have a string of repeated DNA code in the cells of their brain, carrying hundreds to thousands of copies within the gene C9orf72. New research looks at what triggers these repeated sequences to ...

Medical research

Exercise-induced hormone irisin triggers bone remodeling in mice

Exercise has been touted to build bone mass, but exactly how it actually accomplishes this is a matter of debate. Now, researchers show that an exercise-induced hormone activates cells that are critical for bone remodeling ...

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