Investigators at St. Jude Children's Research Hospital have found that the ABCC4 transporter is critical to the SHH signaling pathway in the brain tumor medulloblastoma. This work provides a rationale for development of small ...
Mar 31, 2020
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A surprising discovery about a rare form of childhood brain cancer suggests a new treatment approach for that cancer—and potentially many others.
Feb 13, 2020
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Medication prescribed for a certain type of epilepsy may offer a new method for treating malignant infantile brain tumors. A specific mTOR inhibitor has the ability to cross the blood-brain barrier to both reach and attack ...
Nov 29, 2019
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University of North Carolina Lineberger Comprehensive Cancer Center researchers have identified a potential approach to stop the growth of the most common type of brain tumor in children.
Oct 24, 2019
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A drug used to treat chronic myeloid leukemia appears to be more effective at stopping a type of medulloblastoma in mouse models than existing treatments for the deadly pediatric brain tumor, reports a multi-institutional ...
Sep 20, 2019
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Investigators at St. Jude Children's Research Hospital and Massachusetts General Hospital, alongside others, have revealed the cells of origin for specific subtypes of medulloblastoma, the most common malignant pediatric ...
Jul 24, 2019
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Long-term cognitive problems are a frequent side effect in children undergoing life-saving radiation therapy for medulloblastoma—the most common malignant pediatric brain tumor. Medulloblastoma affects between 250 and 500 ...
Jul 10, 2019
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In 2012, a pair of neurosurgery residents traded their scrubs for lab coats in an effort to understand, at the most basic level, what causes medulloblastoma, the most common pediatric brain cancer.
May 20, 2019
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Scientists are making important progress in the battle against a class of devilishly complex human pediatric brain cancers thanks to a new study from a team of Florida State University students and faculty.
Jan 30, 2019
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Chemotherapy and radiation are effective cancer treatments because they kill rapidly dividing cells, including tumor cells. But for children—whose tiny bodies are still growing—these treatments can cause lifelong damage. ...
Jan 23, 2019
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