Medulloblastoma (the most common malignant childhood brain tumor) is separated into four molecular groups, with Group 3 bearing the worst prognosis. By studying EP300 and CBP, critical proteins in Group 3 medulloblastoma ...
Apr 25, 2024
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A protein that has been widely studied owing to its association with neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS) is also linked to medulloblastoma, a type of central nervous system cancer. Medulloblastoma ...
Feb 7, 2024
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A study of newly created databases of medulloblastoma has found that patients with tumors containing circular extrachromosomal DNA—loops of DNA found outside of regular chromosomes—are twice as likely to relapse and three ...
Nov 14, 2023
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Researchers at Uppsala university have developed a new method to find mutations in brain tumors in children. They also showed that the mutations change how cancer cells respond to a cancer drug. These findings could lead ...
Aug 7, 2023
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New research pinpoints a key cause of metastasis from an aggressive form of brain cancer in children and provides a potential new therapy for treating these tumors in the future.
Mar 6, 2023
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An enzyme that drives the growth of an often-lethal childhood brain cancer may hold the key to a future treatment, says a McMaster University-led study.
Nov 10, 2022
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A deep dive into the proteins and protein activities of human tumors grown in mouse models expands the potential therapeutic pathways to treat medulloblastoma, according to a new study published in the Journal of Proteome ...
Sep 27, 2022
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An aggressive type of pediatric brain tumor, medulloblastoma, exists in a pre-malignant form at birth after initially developing during the first or second trimester of pregnancy, according to a new international study. As ...
Sep 21, 2022
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When MUSC Hollings Cancer Center researcher Jezabel R. Blanco, Ph.D., began studying neurosciences, first as a graduate student and later as a postdoctoral fellow, her research was focused on understanding the mechanisms ...
Jul 21, 2022
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Scientists at St. Jude Children's Research Hospital have identified how an appendage on the surface of cells, called the primary cilium, contributes to certain types of medulloblastoma. The study has implications for drug ...
Jul 8, 2022
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