UNC Lineberger Comprehensive Cancer Center researchers have demonstrated that a novel combination of two drugs that act as targeted inhibitors, delivered in a nanoparticle formulation, extend the survival of mice with medulloblastoma. ...
Jan 26, 2022
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Copper has been clinically improving the lives of people since about 1500 BCE, when an Egyptian physician first recorded its use as a treatment for inflammation. Some 35 centuries later, researchers at Johns Hopkins Medicine ...
Nov 3, 2021
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With advances in medical science driving progress against childhood brain tumors, today three out of four young patients survive at least five years beyond diagnosis. However, the outcomes look grim when malignant cells spread, ...
Jun 29, 2021
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Scientists from Queen Mary University of London, funded by the charity Brain Tumor Research, have found a new way to starve cancerous brain tumor cells of energy in order to prevent further growth.
Apr 12, 2021
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Investigators at St. Jude Children's Research Hospital, the European Molecular Biology Laboratory, and the German Cancer Research Center have identified ELP1 as a novel predisposition gene in the SHH subgroup of pediatric ...
Apr 1, 2020
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A surprising discovery about a rare form of childhood brain cancer suggests a new treatment approach for that cancer—and potentially many others.
Feb 13, 2020
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Medication prescribed for a certain type of epilepsy may offer a new method for treating malignant infantile brain tumors. A specific mTOR inhibitor has the ability to cross the blood-brain barrier to both reach and attack ...
Nov 29, 2019
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A drug used to treat chronic myeloid leukemia appears to be more effective at stopping a type of medulloblastoma in mouse models than existing treatments for the deadly pediatric brain tumor, reports a multi-institutional ...
Sep 20, 2019
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Investigators at St. Jude Children's Research Hospital and Massachusetts General Hospital, alongside others, have revealed the cells of origin for specific subtypes of medulloblastoma, the most common malignant pediatric ...
Jul 24, 2019
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Chemotherapy and radiation are effective cancer treatments because they kill rapidly dividing cells, including tumor cells. But for children—whose tiny bodies are still growing—these treatments can cause lifelong damage. ...
Jan 23, 2019
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