Diseases, Conditions, Syndromes

SARS-CoV-2 spike protein alone may cause lung damage

Using a newly developed mouse model of acute lung injury, researchers found that exposure to the SARS-CoV-2 spike protein alone was enough to induce COVID-19-like symptoms including severe inflammation of the lungs.

Genetics

Gene changes might explain long-haul COVID-19 symptoms

Results from a new cell study suggest that the SARS-CoV-2 spike protein can bring about long-term gene expression changes. The findings could help explain why some COVID-19 patients—referred to as COVID long-haulers—experience ...

Surgery

Researchers work to increase number of transplantable livers

Thousands of livers donated for transplantation are discarded or turned down every year due to concerns about organ quality and function. New insights into why these organs are considered unusable and how they function during ...

Medications

Could heart medications increase COVID-19 risk?

During infection, SARS-CoV-2 binds to a cellular receptor known as angiotensin converting enzyme 2 (ACE2) before entering a cell and replicating. Because it is not well established whether common blood pressure medications ...

Diseases, Conditions, Syndromes

Toward a feasible alternative to liver organ transplant

New insights into how fetal and adult liver cells differ could be used to help make liver cell transplants successful long term. Transplanting functioning liver cells into a patient's liver can help replace liver function ...

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