Oncology & Cancer

How immune cells in the tumor microenvironment make things worse

Cells from the immune system called CD4+ regulatory T cells, or simply Treg, are linked to tumor prognosis: the more Treg cells present in a tumor, the worst the prognosis. We know from previous research studies that Treg ...

Oncology & Cancer

Skin cancer app fails to identify rare, aggressive cancers

(HealthDay)—A direct-to-consumer machine learning model for detecting skin cancers may not adequately recognize rare, but aggressive, skin cancers, according to a study presented at the annual meeting of the European Academy ...

Oncology & Cancer

CAR-T immunotherapy could be improved to kill solid tumors

Immunotherapy, which harnesses the power of the body's immune system to fight disease, is gaining huge traction in treating cancer. Chief among cancer immunotherapies is a treatment known as CAR-T, or chimeric antigen receptor ...

Immunology

Why don't adrenal gland metastases respond to immunotherapy?

Recent advances in immunotherapy have allowed doctors at the University of Colorado Cancer Center to more effectively treat melanomas that spread to other parts of the body. Immunotherapy drugs such as checkpoint inhibitors, ...

Oncology & Cancer

New nano particles suppress resistance to cancer immunotherapy

Hokkaido University scientists and colleagues in Japan have found a way that could help some patients overcome resistance to an immunotherapy treatment for cancer. The approach, proven in mice experiments, was reported in ...

Oncology & Cancer

Study reveals source of DNA mutations in melanoma

The mutations that give rise to melanoma result from a chemical conversion in DNA fueled by sunlight—not just a DNA copying error as previously believed, reports a study by Van Andel Institute scientists published today ...

Oncology & Cancer

Antibiotics may help to treat melanoma

Some antibiotics appear to be effective against a form of skin cancer known as melanoma. Researchers at KU Leuven, Belgium, examined the effect of these antibiotics on patient-derived tumors in mice. Their findings were published ...

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