Oncology & Cancer

A newly discovered tumor suppressor gene affects melanoma survival

Of the hundreds of genes that can be mutated in a single case of melanoma, only a handful may be true "drivers" of cancer. In research that appeared last week in Nature Genetics, a Weizmann Institute of Science team has now ...

Oncology & Cancer

Researchers offer new insights on cancer cell signaling

(Medical Xpress)—A pair of studies by a team of University of Notre Dame researchers led by Crislyn D'Souza-Schorey, professor of biological sciences, sheds light on a biological process that is activated across a vast ...

Medical research

Researchers identify one driver of melanoma spread

Using a small noncoding RNA, microRNA 211, and tools that track the stability and decay of the protein-coding and noncoding RNAs in lab-grown melanoma cells, a team led by a Johns Hopkins Kimmel Cancer Center researcher identified ...

Oncology & Cancer

Changing cancer care, one organoid at a time

A patient-specific tumor organoid platform developed by Wake Forest Institute for Regenerative Medicine (WFIRM) researchers and their cancer center colleagues could someday take the guessing game out of immunotherapy treatments. ...

Oncology & Cancer

P Rex-1 protein key to melanoma metastasis

Researchers from UNC Lineberger Comprehensive Cancer Center are part of a team that has identified a protein, called P-Rex1, that is key to the movement of cells called melanoblasts. When these cells experience uncontrolled ...

Oncology & Cancer

Study links genetic mutation and melanoma progression

Dartmouth researchers have found that the genetic mutation BRAFV600E, frequently found in metastatic melanoma, not only secretes a protein that promotes the growth of melanoma tumor cells, but can also modify the network ...

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