Drugmaker Bristol-Myers Squibb Co. is expanding its collaboration with Five Prime Therapeutics Inc., which could receive more than $1.75 billion if they succeed in turning Five Prime's antibody-based drug candidates into ...
Oct 15, 2015
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Melanoma is the least common but one of the most deadly skin cancers. It accounts for only about one percent of all cases globally, but the majority of skin cancer deaths. Accurate, timely and reliable diagnosis of cutaneous ...
Sep 30, 2019
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Single-cell analysis is a groundbreaking approach now being used across biological fields to explore a common problem: how to study cellular diversity in cell environments with heterogeneous populations. Such diversity can ...
Apr 8, 2016
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Cancer-associated fibroblasts (CAFs) are key factors in the tumor microenvironment, which have been implicated in cancer cell progression. It has also been reported that vesicles called exosomes produced by these CAFs play ...
Mar 28, 2023
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While past attempts to treat melanoma failed to meet expectations, an international team of researchers are hopeful that a compound they tested on both mice and on human cells in a petri dish takes a positive step toward ...
Jul 26, 2017
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A new approach demonstrated that the recognition of unique cancer mutations appeared to be responsible for complete cancer regressions in two metastatic melanoma patients treated with a type of immunotherapy called adoptive ...
Jul 1, 2014
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Metastatic melanoma is the leading cause of skin cancer deaths in the United States; once melanoma has spread (metastasized), life expectancy for patients can be dramatically shortened. At present, the reference therapy for ...
Mar 13, 2015
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Changes in the structure of the skin and the lymphatic system that occur with the natural aging process create permissive conditions for melanoma metastasis, according to two studies by The Wistar Institute. These changes ...
Oct 2, 2018
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Cancer cell spread to the sentinel node—the lymph node to which cancer cells are most likely to spread from a primary tumor—is a risk factor for melanoma death. According to a study published in this week's PLOS Medicine ...
Feb 18, 2014
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There's a reason why melanoma, the most serious type of skin cancer, is so aggressive. You just need to watch the cells in action.
Apr 3, 2017
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