Medical research

Understanding and improving the body's fight against pathogens

Scientists from A*STAR's Bioprocessing Technology Institute (BTI) have uncovered the crucial role of two signalling molecules, DOK3 and SHP1, in the development and production of plasma cells. These discoveries, published ...

Medical research

Sugary bugs subvert antibodies

A lung-damaging bacterium turns the body's antibody response in its favor, according to a study published in The Journal of Experimental Medicine.

Medical research

Unlocking the therapeutic potential of SLC13 transporters

Researchers have provided the first functional analysis of a member of a family of transporter proteins implicated in diabetes, obesity, and lifespan. The study appears in the June issue of The Journal of General Physiology.

Medical research

Unexpected player in regulation of blood cholesterol levels

Kinesins are motor proteins that "walk" along microtubules and transport various cargoes throughout the cell. A study in The Journal of Cell Biology uncovers an unexpected role for one kinesin in the pathway that regulates ...

Medical research

Identifying a mystery channel crucial for hearing

Our ability to hear relies on hair cells, sensory receptors that mechanically amplify low-level sound that enters the inner ear through a transduction channel. Although the transduction channel was characterized more than ...

Medical research

Life in a bubble: Nobel secrets of body's cell transport system

Vesicles, the bubble-shaped vessels that transport molecules within cells, may hold the secret to halting viruses or even combating Alzheimer's, say experts who hailed Monday's Nobel awarded to three leaders in the field.

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