(Medical Xpress) -- The multidrug transporter EmrE functions as an asymmetric antiparallel dimer (molecule with two subunits). Drug (blue) transport from the inside to the outside of the cell membrane is accomplished by exchange ...
Jan 31, 2012
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Metastasizing cancer cells often express integrins that provide better traction. A new study in The Journal of Cell Biology reveals how a lipid-converting enzyme helps the cells mobilize these integrins.
Jan 23, 2012
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A team of researchers led by Kasturi Haldar and Souvik Bhattacharjee of the University of Notre Dame's Center for Rare and Neglected Diseases has made a fundamental discovery in understanding how malaria parasites cause deadly ...
Jan 20, 2012
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Researchers at the University of Iowa have worked out the exact function of an enzyme that is critical for normal muscle structure and is involved in several muscular dystrophies. The findings, which were published Jan. 6 ...
Jan 9, 2012
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Half the drugs used today target a single class of proteins – and now scientists have identified an important molecular player critical to the proper workings of those proteins critical to our health.
Dec 27, 2011
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Scientists studying how mammals detect microbes have discovered new components in a crucial pathway that allows immune cells to detect viral invaders. Their research not only deepens the understanding of antiviral responses, ...
Dec 22, 2011
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Drawing on X-ray crystallography and experimental data, as well as a software suite for predicting and designing protein structures, a UC Davis School of Medicine researcher has developed an algorithm that predicts what has ...
Dec 12, 2011
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Scientists at Warwick Medical School have made an important discovery about the mechanism controlling the body's 'fat switch', shedding new light on our understanding of how proteins regulate appetite control and insulin ...
Dec 8, 2011
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Sluggish recycling of a protein-slicing enzyme could promote Alzheimer's disease, according to a study published online on November 21 in The Journal of Cell Biology.
Nov 21, 2011
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Each time a cell divides -- and it takes millions of cell divisions to create a fully grown human body from a single fertilized cell -- its chromosomes have to be accurately divvied up between both daughter cells. Researchers ...
Nov 17, 2011
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