Immunology

How immune cells kill bacteria with acid

The first line of immune defense against invading pathogens like bacteria are macrophages, immune cells that engulf foreign objects that cross their way. After enclosing them in intracellular membrane vesicles, a process ...

Alzheimer's disease & dementia

Astrocyte findings suggest new options against Alzheimer's

A study by scientists of the German Center for Neurodegenerative Diseases (DZNE) points to a potential approach against Alzheimer's disease. In studies with mice, the researchers were able to show that blocking a particular ...

Diseases, Conditions, Syndromes

Hitting virus infections where it hurts

Virus infection starts at the cell surface with interactions between viral and host proteins that bind together. Researchers are working on ways to lock out the virus or prevent it from reproducing in the cell by targeting ...

Medical research

Experimental drug extends survival in progeria

A report from a clinical trial for a drug to treat the rapid-aging disorder progeria, published in this week's Journal of the American Medical Association, offers hope for families with the ultra-rare genetic condition.

Immunology

Toxin floats on lipid rafts

Helicobacter pylori, the leading cause of peptic ulcer disease and stomach cancer. One factor important to H. pylori infection is the pore-forming toxin VacA. It is thought to gain entry into host cells by binding to specialized ...

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