Oncology & Cancer

Number of mesothelioma deaths up among women from 1999 to 2020

From 1999 to 2020, there was an increase in the annual number of mesothelioma deaths among women, although the age-adjusted death rate decreased, according to research published in the May 13 issue of the U.S. Centers for ...

Oncology & Cancer

Gene x environment interactions may help reduce mesothelioma risk

Researchers have recently discovered that certain enzymes binded to each other may help lessen the risk of developing mesothelioma, a cancer of the lining of the lungs and abdomen. The study from University of Hawaiʻi Cancer ...

Diseases, Conditions, Syndromes

1990 to 2017 saw increase in global incidence of mesothelioma

(HealthDay)—Incident cases of mesothelioma and deaths associated with mesothelioma increased worldwide during 1990 to 2017, according to a study published online Aug. 11 in JAMA Network Open.

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Mesothelioma

Mesothelioma, more precisely malignant mesothelioma, is a rare form of cancer that develops from the protective lining that covers many of the body's internal organs, the mesothelium. It is usually caused by exposure to asbestos.

Its most common site is the pleura (outer lining of the lungs and internal chest wall), but it may also occur in the peritoneum (the lining of the abdominal cavity), the pericardium (a sac that surrounds the heart), or the tunica vaginalis (a sac that surrounds the testis).

Most people who develop mesothelioma have worked on jobs where they inhaled asbestos, or they have been exposed to asbestos dust and fiber in other ways. It has also been suggested that washing the clothes of a family member who worked with asbestos can put a person at risk for developing mesothelioma. Unlike lung cancer, there is no association between mesothelioma and smoking, but smoking greatly increases the risk of other asbestos-induced cancers. Those who have been exposed to asbestos have collected damages for asbestos-related disease, including mesothelioma. Compensation via asbestos funds or lawsuits is an important issue in law practices regarding mesothelioma (see asbestos and the law).

The symptoms of mesothelioma include shortness of breath due to pleural effusion (fluid between the lung and the chest wall) or chest wall pain, and general symptoms such as weight loss. The diagnosis may be suspected with chest X-ray and CT scan, and is confirmed with a biopsy (tissue sample) and microscopic examination. A thoracoscopy (inserting a tube with a camera into the chest) can be used to take biopsies. It allows the introduction of substances such as talc to obliterate the pleural space (called pleurodesis), which prevents more fluid from accumulating and pressing on the lung. Despite treatment with chemotherapy, radiation therapy or sometimes surgery, the disease carries a poor prognosis. Research about screening tests for the early detection of mesothelioma is ongoing.

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