Peter Szlosarek, Professor of Medical Oncology at Queen Mary's Barts Cancer Institute, presented his team's results from the ATOMIC-Meso clinical trial in partnership with Polaris Pharmaceuticals, Inc., at the American Association ...
Apr 18, 2023
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Treatment outcomes for patients with malignant pleural mesothelioma, a rare cancer commonly known as mesothelioma, are often affected by social determinants of health, and overall survival rates could be improved by addressing ...
Mar 23, 2023
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In a study published recently in the journal Clinical Cancer Research, researchers at Baylor College of Medicine found that treating patients who have resectable malignant pleural mesothelioma, meaning that their tumor can ...
Dec 13, 2022
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A new study has investigated the expression of the primary cilium in mesothelioma, finding that primary cilia is preferentially lost in the more aggressive subtype of mesothelioma and further research may confirm its potential ...
Oct 27, 2022
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Rice University and Baylor College of Medicine researchers have shown they can eradicate advanced-stage mesothelioma tumors in mice in just a few days with a treatment combining Rice's cytokine "drug factory" implants and ...
Aug 22, 2022
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Mesotheliomas are very aggressive tumors, almost exclusively caused by asbestos, which are very often occupational. Between 2014 and 2020, four out of five cases of testicular mesothelioma assessed at an institute were recognized ...
Jun 23, 2022
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From 1999 to 2020, there was an increase in the annual number of mesothelioma deaths among women, although the age-adjusted death rate decreased, according to research published in the May 13 issue of the U.S. Centers for ...
May 13, 2022
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Researchers at the University of Colorado Anschutz Medical Campus and their international collaborators have discovered that a protein critical in the embryonic stages of life is reactivated in certain cases of mesothelioma, ...
Mar 30, 2022
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Researchers have recently discovered that certain enzymes binded to each other may help lessen the risk of developing mesothelioma, a cancer of the lining of the lungs and abdomen. The study from University of Hawaiʻi Cancer ...
Dec 3, 2021
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The PrE0505 phase 2 clinical trial results are published in the November 8 issue of Nature Medicine. The study evaluated the addition of durvalumab immunotherapy to standard chemotherapy in patients with previously untreated, ...
Nov 8, 2021
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Mesothelioma, more precisely malignant mesothelioma, is a rare form of cancer that develops from the protective lining that covers many of the body's internal organs, the mesothelium. It is usually caused by exposure to asbestos.
Its most common site is the pleura (outer lining of the lungs and internal chest wall), but it may also occur in the peritoneum (the lining of the abdominal cavity), the pericardium (a sac that surrounds the heart), or the tunica vaginalis (a sac that surrounds the testis).
Most people who develop mesothelioma have worked on jobs where they inhaled asbestos, or they have been exposed to asbestos dust and fiber in other ways. It has also been suggested that washing the clothes of a family member who worked with asbestos can put a person at risk for developing mesothelioma. Unlike lung cancer, there is no association between mesothelioma and smoking, but smoking greatly increases the risk of other asbestos-induced cancers. Those who have been exposed to asbestos have collected damages for asbestos-related disease, including mesothelioma. Compensation via asbestos funds or lawsuits is an important issue in law practices regarding mesothelioma (see asbestos and the law).
The symptoms of mesothelioma include shortness of breath due to pleural effusion (fluid between the lung and the chest wall) or chest wall pain, and general symptoms such as weight loss. The diagnosis may be suspected with chest X-ray and CT scan, and is confirmed with a biopsy (tissue sample) and microscopic examination. A thoracoscopy (inserting a tube with a camera into the chest) can be used to take biopsies. It allows the introduction of substances such as talc to obliterate the pleural space (called pleurodesis), which prevents more fluid from accumulating and pressing on the lung. Despite treatment with chemotherapy, radiation therapy or sometimes surgery, the disease carries a poor prognosis. Research about screening tests for the early detection of mesothelioma is ongoing.
This text uses material from Wikipedia, licensed under CC BY-SA
