Gene therapy targeting the messenger RNA (mRNA) of the mutated huntingtin gene (HTT) can provide long-lasting therapeutic benefit in Huntington's disease after a single administration. An adeno-associated virus (AAV) gene ...
Jan 25, 2022
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Investigators from the Smidt Heart Institute at Cedars-Sinai have identified how biological pacemaker cells—cells that control your heartbeat—can "fight back" against therapies to biologically correct abnormal heartbeat ...
Dec 20, 2022
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In solving one mystery—the genetic roots of benign brain tumors called meningiomas—a team of scientists led by Yale researchers stumbled upon an even greater one: How is it possible that two of the mutations linked to ...
Aug 23, 2016
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Ten days after receiving a second dose of a messenger RNA, or mRNA, vaccine for COVID-19, patients without COVID-19 symptoms are far less likely to test positive and unknowingly spread COVID-19, compared to patients who have ...
Mar 11, 2021
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The coronavirus pandemic has made vaccines from Pfizer/BioNTech and Moderna and the mRNA technology that they use into household names.
Oct 15, 2021
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A three molecule complex may be a target for treating Huntington's disease, a genetic disorder affecting the brain. This finding by an international research team including scientists from the German Center for Neurodegenerative ...
Feb 26, 2013
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Vaccines have played a major role in mitigating the harms of the COVID pandemic since their rollout began just over two years ago. They're estimated to have saved tens of millions of lives across the globe.
Jan 11, 2023
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Many heritable immune diseases such as rheumatoid arthritis and blood-cell related traits derive from critical proteins not being made or not functioning correctly. But exactly how a person's genes, the regulation of these ...
Jul 7, 2020
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University of Louisville researchers have replicated the inflammatory gene changes of a human kidney as it progresses from mild to severe diabetic nephropathy, using a mouse model developed by a UofL researcher, according ...
May 23, 2011
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The Molecular Neuroscience Unit at the Okinawa Institute of Science and Technology (OIST) has made an important breakthrough by connecting sensory neurons' survival and pathology with the way messenger RNAs (mRNAs) are transported ...
Oct 31, 2023
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