Oncology & Cancer

New understanding of how faulty metabolism triggers adrenal cancer

Researchers have deciphered a signaling cascade through which inborn errors in metabolism provoke deadly neuroendocrine tumors in the adrenal glands. This discovery explains how impaired metabolism due to mutations in a key ...

Diabetes

Exenatide does not promote weight loss in schizophrenia

(HealthDay)—For antipsychotic-treated obese patients with schizophrenia, glucagon-like peptide-1 receptor agonists (GLP-1RAs) do not appear to promote weight loss, according to a study published online Sept. 26 in Diabetes, ...

Medical research

Researchers identify new vitamin B3 pathway

Researchers at Beth Israel Deaconess Medical Center (BIDMC) have identified a new vitamin B3 pathway that regulates liver metabolism. The discovery provides an opportunity to pursue the development of novel drug therapies ...

Neuroscience

Getting a grip on sleep

All mammals sleep, as do birds and some insects. However, how this basic function is regulated by the brain remains unclear. According to a new study by researchers from the RIKEN Brain Science Institute, a brain region called ...

Health

How a low-calorie diet could extend lifespan

Overeating can lead to health issues that can shorten one's life, such as obesity, diabetes and heart disease. On the other end of the spectrum, several studies have shown that restricting calorie intake below what a normal ...

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