Medical research

Deciphering pancreatic cancer's invade and evade tactics

Two known gene mutations induce pathways that enhance pancreatic cancer's ability to invade tissues and evade the immune system. Researchers report the molecular details of this process, providing insights into druggable ...

Diabetes

New insight into the biology of insulin release

In a new study, Yale researchers challenge a long-held assumption about how insulin-producing cells in the pancreas sense and respond to glucose. Their findings could lead to changes in the way that scientists approach the ...

Medical research

A tale of two proteins: The best and worst of metabolic adaptation

The Developmental Origins of Health and Disease (DOHaD) hypothesis is supported by multiple human epidemiological studies and animal studies. It states that the nutritional environment in early life makes people susceptible ...

Medical research

Researchers discover new pathway for improving metabolic health

Blocking the action of an enzyme involved in protein digestion may improve metabolic health, according to a new study published ahead of print in the American Journal of Physiology—Gastrointestinal and Liver Physiology. ...

Immunology

Challenging metabolism may help fight disease

New research by Swansea University academics has shown that harnessing metabolism at a cellular level may help to relieve or heal a range of disorders.

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