Diseases, Conditions, Syndromes

Researchers link environmental exposures to liver disease

Mayo Clinic researchers have identified a diverse range of environmental chemicals in human bile in patients with primary sclerosing cholangitis, a rare, chronic liver disease of the bile ducts. The study, published in Exposome, ...

Inflammatory disorders

Study may explain why high-sugar diets can worsen IBD

Excess sugar hampers cells that renew the colon's lining in a mouse model of inflammatory bowel disease (IBD), according to a new study by University of Pittsburgh scientists.

Medical research

Cells can use uridine, a component of RNA, as a source of energy

Our bodies burn carbohydrates, proteins, and fat for fuel, and now, researchers at the Broad Institute of MIT and Harvard and the University of Lausanne have discovered another important energy source for cells: uridine, ...

Oncology & Cancer

Gamma delta T cells can fight aggressive breast cancer

Triple-negative breast cancer (TNBC) is the most aggressive and deadly form of breast cancer with limited treatment options and a high probability of recurrence. Tumor growth and relapse of TNBC are driven by breast cancer ...

Health

How does the body clock keep track of time?

Picture the scene: you wake up in the dim light of the morning, and wonder if it's already time to get up. Just as you reach for your bedside clock, your morning alarm goes off. It's a handy—if mysterious—skill. But how ...

Gerontology & Geriatrics

'Beige fat' could hold key to age-related metabolism change

New research suggests a strategy to ward off age-related weight gain, which could prevent obesity and associated health disorders like type 2 diabetes, heart disease and chronic inflammation.

Oncology & Cancer

Alternative glucose breakdown ensures the survival of cancer cells

A key enzyme in sugar metabolism is inactivated particularly easily and efficiently by oxidative stress. Scientists at the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) have now shown that with this ...

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