Acute myocardial infarction (AMI) causes a massive loss of cardiomyocytes, leading to heart failure with fibrosis, stiffening of the heart and loss of function. Diabetes mellitus (DM) is a well-known risk factor for AMI. ...
Feb 10, 2023
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Neuropathic pain is a type of chronic pain caused by damage to the nervous system due mainly to metabolic diseases such as diabetes and arthritis, or the side effects of some kinds of chemotherapy. It is believed to affect ...
Jan 10, 2023
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Lactate, a major product of glycolysis in mammals, is significantly increased in pathological states such as tumors, sepsis and autoimmune diseases, which is known as the Warburg effect. Despite being an important metabolic ...
Jan 4, 2023
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A research team at LKS Faculty of Medicine, The University of Hong Kong (HKUMed) has discovered that high glucose impairs the anti-tumor activity of immune effector gamma delta T cells (γδ-T cells), which contributes to ...
Nov 29, 2022
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A recent study in The FASEB Journal has identified metabolic perturbations in the liver and skeletal muscle of young nonhuman primates on normal diets whose mothers were obese during pregnancy.
Nov 23, 2022
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As differently as cancers or autoimmune diseases (such as multiple sclerosis, rheumatoid arthritis or psoriasis) affect people, they all have one characteristic in common: they are accompanied by increased cell proliferation. ...
Nov 14, 2022
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Disruptions in the gut microbiome have been linked to lower survival rates for people who have undergone kidney and liver transplants, a finding that highlights the critical importance of the vast and complex microbial communities ...
The way that tumor cells enable their uncontrolled growth is also a weakness that can be harnessed to treat cancer, researchers at the University of Michigan and Indiana University have shown.
Sep 21, 2022
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Patients who suffer from a form of raised brain pressure could have their condition identified earlier thanks to new metabolic clues, new research has found.
Sep 8, 2022
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The locus coeruleus is among the first brain regions to degenerate in Alzheimer's and Parkinson's disease, physicians and scientists have known. But why this area is so vulnerable is less understood.
Sep 1, 2022
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