Oncology & Cancer

New study shows how cells can be led down non-cancer path

As cells with a propensity for cancer break down food for energy, they reach a fork in the road: They can either continue energy production as healthy cells, or shift to the energy production profile of cancer cells. In a ...

Oncology & Cancer

Study challenges long-standing concept in cancer metabolism

Scientists at the Children's Medical Center Research Institute at UT Southwestern (CRI) have discovered that lactate provides a fuel for growing tumors, challenging a nearly century-old observation known as the Warburg effect.

Diseases, Conditions, Syndromes

Faulty gene linked to obesity in adults

Groundbreaking new research linking obesity and metabolic dysfunction to a problem in the energy generators in cells has been published by researchers from the Harry Perkins Institute of Medical Research and The University ...

Oncology & Cancer

Metabolism drives growth and division of cancer cells

The metabolic state of tumor cells contributes to signals that control their proliferation. German biochemist and Nobel Prize laureate Otto H. Warburg observed in the 1920s that tumor cells radically change their metabolism. ...

Cardiology

Cholesterol—Good for the brain, bad for the heart

Healthy brains need plenty of cholesterol for nerve cells to grow and work properly, but diabetes can reduce the amount of cholesterol in the brain, as a Joslin Diabetes Center team has demonstrated. Joslin researchers and ...

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