Overweight & Obesity

A drug already in use in humans corrects obesity in mice

It has long been known that obesity is an inflammatory disease, i.e. a chronic defensive reaction of the body to stress caused by excess nutrients. Based on this knowledge, a group of researchers led by Nabil Djouder, head ...

Gastroenterology

How the gut microbiota develops in the first five years of life

The human gut microbiota largely reaches an adult-like composition by five years of age, but important differences remain, finds a study published on March 31st in the journal Cell Host & Microbe. Several bacterial taxa that ...

Immunology

Molecular 'switch' reverses chronic inflammation and aging

Chronic inflammation, which results when old age, stress or environmental toxins keep the body's immune system in overdrive, can contribute to a variety of devastating diseases, from Alzheimer's and Parkinson's to diabetes ...

Medical research

New drug helps combat metabolic syndrome

A new drug developed at Yale reduces a host of abnormalities associated with metabolic syndrome, an obesity-born condition that afflicts one of three adults in the United States, researchers report Oct. 2 in the journal Science ...

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