Diabetes

NASH-linked changes impact metformin pharmacokinetics

(HealthDay)—Nonalcoholic steatohepatitis (NASH)-associated changes in liver function affect kidney transporter expression and metformin pharmacokinetics, according to an experimental study published online May 27 in Diabetes ...

Diabetes

Concomitant metformin, GERD meds up vitamin B12 depletion

(HealthDay)—Concomitant use of metformin and histamine H2-receptor antagonists or proton pump inhibitors has the potential to induce vitamin B12 depletion and neuropathy, according to research published in the April issue ...

Oncology & Cancer

Metformin use may not improve pancreatic cancer survival

Metformin use did not improve survival of patients with pancreatic ductal adenocarcinoma (PDAC) in a retrospective cohort study, according to data presented at the AACR Annual Meeting 2015, April 18-22.

Oncology & Cancer

Metformin use associated with less CRC risk in US population

(HealthDay)—For patients with diabetes in the United States, metformin use is associated with reduced risk of developing colorectal cancer (CRC), according to a study published in the April 1 issue of Cancer.

Oncology & Cancer

Metformin may lower lung cancer risk in diabetic nonsmokers

Among nonsmokers who had diabetes, those who took the diabetes drug metformin had a decrease in lung cancer risk, according to a study in Cancer Prevention Research, a journal of the American Association for Cancer Research,by ...

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