Medical research

Researchers identify novel pathways responsible for liver cancer

Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer. It is one of leading causes of cancer-related deaths globally, with more than 700,000 new cases and 600,000 estimated HCC deaths each year. HCC ...

Oncology & Cancer

Study shows epigenetic changes can drive cancer

Cancer has long been thought to be primarily a genetic disease, but in recent decades scientists have come to believe that epigenetic changes – which don't change the DNA sequence but how it is 'read' – also play a role ...

Oncology & Cancer

Scientists reveal how mutations in metabolism can drive cancers

Our cells have several ways to repair DNA that breaks when the cells divide. However, genetic mutations can disable these DNA repair mechanisms, destabilize the cells, and trigger cancer. In a paper published today in the ...

Oncology & Cancer

Liquid biopsy may be new way to detect liver cancer earlier, easier

An international team of researchers at University of California San Diego School of Medicine and Moores Cancer Center, with colleagues at Sun Yet-sun University Cancer Center and other collaborating institutions, have developed ...

Genetics

Intestinal microbes reprogram genetic activity of gut mucosa

Scientists from the German Cancer Research Center and the Hebrew University in Jerusalem demonstrated in mice that intestinal bacteria reprogram DNA activity in cells of the gut mucosa and thus have a considerable impact ...

Oncology & Cancer

New target found to attack an incurable brain tumor in children

A study published in Molecular Cancer Research reveals that a tumor suppressor gene p16 is turned off by a histone mutation (H3.3K27M), which is found in up to 70 percent of childhood brain tumors called diffuse intrinsic ...

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