Neuroscience

Childhood trauma leaves mark on DNA of some victims

Abused children are at high risk of anxiety and mood disorders, as traumatic experience induces lasting changes to their gene regulation. Scientists from the Max Planck Institute of Psychiatry in Munich have now documented ...

Oncology & Cancer

Cancer cells' universal 'dark matter' exposed

Using the latest gene sequencing tools to examine so-called epigenetic influences on the DNA makeup of colon cancer, a Johns Hopkins team says its results suggest cancer treatment might eventually be more tolerable and successful ...

Oncology & Cancer

13 special genes linked to epigenetic changes in cancer samples

Reducing the burden of cancer in individuals and society is a major area of concern globally. In Norway, by the end of 2020, 35,515 people were newly diagnosed with cancer and more than 300,000 people were already living ...

Immunology

Immune cells turn back time to achieve memory

Memory T cells earn their name by embodying the memory of the immune system - they help the body remember what infections or vaccines someone has been exposed to. But to become memory T cells, the cells go backwards in time, ...

Oncology & Cancer

Researchers erase human brain tumor cells in mice

Working with mice, Johns Hopkins researchers have discovered that weeks of treatment with a repurposed FDA-approved drug halted the growth of—and ultimately left no detectable trace of—brain tumor cells taken from adult ...

Genetics

Mom's in control—even before you're born

Researchers have uncovered previously unappreciated means by which epigenetic information contained in the egg influences the development of the placenta during pregnancy. The research, which was performed in mice, indicates ...

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