Diseases, Conditions, Syndromes

Huntington's Disease: Neural traffic could help understand the disease

Huntington's disease is a genetic neurodegenerative disorder caused by mutations in the protein huntingtin and characterized by involuntary dance-like movements, severe behavioral changes and cognitive impairment. That neuronal ...

Neuroscience

DNA damage 'hot spots' discovered within neurons

Researchers at the National Institutes of Health (NIH) have discovered specific regions within the DNA of neurons that accumulate a certain type of damage (called single-strand breaks or SSBs). This accumulation of SSBs appears ...

Oncology & Cancer

Aggregated waste in brain tumors predict disease severity

Proteins are crucial to all cellular processes. So for a cell to stay viable, it has to keep its proteins in shape. In technical terms, it's called protein folding, and it refers to the process by which proteins assume their ...

Medical research

Changing the perspective on the 'Cinderella of the cytoskeleton'

SETD2 is a protein well known as a chromatin remodeler, one that helps turn genes on or off by modifying histone proteins in the nucleus of the cell. When researchers discovered that SETD2 is mutated or lost in several cancer ...

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