For more than a decade, scientists have had a working map of the human genome, a complete picture of the DNA sequence that encodes human life. But new pages are still being added to that atlas: maps of chemical markers called ...
Jun 1, 2015
5
127
A Purdue University study sheds light on how cell damage is reversed by the cancer drug decitabine and identifies a potential biomarker that could indicate a patient's stage of cancer and response to treatment.
Apr 22, 2015
0
74
Dirk Schübeler and his group at the Friedrich Miescher Institute for Biomedical Research (FMI) identify determinants that set epigenetic marks along the genome. The new study, published in Nature, shows that genetic activity ...
Feb 10, 2015
8
76
The genetic tumult within cancerous tumors is more than matched by the disorder in one of the mechanisms for switching cells' genes on and off, scientists at Dana-Farber Cancer Institute and the Broad Institute of MIT and ...
Dec 8, 2014
0
0
In 1957, Conrad Waddington published a landmark essay collection that explained a concept he called "the epigenetic landscape."
Sep 2, 2014
0
0
Regardless of their stage or type, cancers appear to share a telltale signature of widespread changes to the so-called epigenome, according to a team of researchers. In a study published online in Genome Medicine on Aug. ...
Aug 25, 2014
1
0
The tiny addition of a chemical mark atop a gene that is well known for its involvement in clinical depression and posttraumatic stress disorder can affect the way a person's brain responds to threats, according to a new ...
Aug 3, 2014
5
0
When a pregnant mother is undernourished, her child is at a greater than average risk of developing obesity and type 2 diabetes, in part due to so-called 'epigenetic' effects. A new study in mice demonstrates that this 'memory' ...
Jul 10, 2014
1
1
Disturbed patterns of blood flow induce lasting epigenetic changes to genes in the cells that line blood vessels, and those changes contribute to atherosclerosis, researchers have found. The findings suggest why the protective ...
May 27, 2014
0
0
Chromosomes are heavily adorned with methyl chemical groups that alter the activity of nearby genes. The parental chromosomes, contributed by sperm and egg, display distinctly different methylation patterns and most modifications ...
Jan 15, 2014
0
0
