Lung cancer remains a leading global health concern, responsible for the highest number of cancer-related deaths worldwide. Central to its development is the tumor microenvironment, which involves a complex interplay with ...
May 15, 2024
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The Wistar Institute assistant professor Filippo Veglia, Ph.D., and team, have discovered a key mechanism of how glioblastoma—a serious and often fatal brain cancer—suppresses the immune system so that the tumor can grow ...
May 3, 2024
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Adding a pre-ketone supplement—a component of a high-fat, low-carb ketogenic diet—to a type of cancer therapy in a laboratory setting was highly effective for treating prostate cancer, researchers from the University ...
Apr 27, 2024
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Tumor-resident microbiota in breast cancer promotes both the initiation and progression of cancer. However, the potential of targeting microbiota to enhance the efficacy of breast cancer treatment has not been comprehensively ...
Apr 25, 2024
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In the past decade, immunotherapy has emerged as the fourth pillar of cancer treatment, joining surgery, radiotherapy and chemotherapy. It is an approved treatment for 15 cancers, including melanoma and some types of lymphomas ...
Apr 22, 2024
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Esophageal squamous cell carcinoma (ESCC) accounts for around 90% of esophageal cancers, especially in East Asia. New findings indicate that periostin, or POSTN, promotes ESCC progression by enhancing cancer and stromal cell ...
Apr 9, 2024
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A recent Northwestern Medicine study has discovered a previously unknown molecular mechanism that supports antitumor responses and cell survival in cytotoxic immune cells, according to findings published in the Journal of ...
Apr 9, 2024
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In a small, investigator-initiated Phase II study by Dana-Farber Cancer Institute investigators, a novel combination of an antibody-drug conjugate and an immune checkpoint inhibitor showed notable activity in pre-treated ...
Apr 5, 2024
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Like alien invaders in a sci-fi movie, pancreatic cancer cells quickly adapt to the weapons used against them and find ways to survive, even in the harshest of conditions.
Apr 4, 2024
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Hypoxia-activated prodrugs (HAPs) have the potential to activate specifically in hypoxic tumors and eliminate tumor cells, which has brought new opportunities for safe and effective anticancer therapy. However, their therapeutic ...
Apr 3, 2024
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