Inserting a specific strain of bacteria into the microenvironment of aggressive ovarian cancer transforms the behavior of tumor cells from suppression to immunostimulation, researchers at Norris Cotton Cancer Center and the ...
Feb 4, 2015
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Researchers at Sanford Burnham Prebys Medical Discovery Institute (SBP) and UC San Diego have shown that tumors can ensure a more reliable nutrient supply by eliminating the p62 protein in surrounding stromal tissue. Specifically, ...
Oct 6, 2017
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A symposium aiming to provide a better understanding of the tumor microenvironment, immune tolerogenic niches at cancer initiation, and novel immunotherapeutic strategies in head and neck cancer patients was featured at the ...
Mar 19, 2023
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Most immunotherapies, which aim to boost T cell activity, work poorly in treating estrogen receptor-positive (ER+) breast cancer. Targeting a different type of immune cell called macrophages could be a more effective approach, ...
Mar 16, 2023
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Using real-time, high-resolution imaging, scientists have identified how a "doorway" in the blood vessel wall allows cancer cells to spread from breast tumors to other parts of the body. The findings lend support to emerging ...
Aug 12, 2015
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Imagine developing a drug designed to inhibit a protein that helps cancer cells proliferate and survive only to find that the drug does not perform very well in the clinic. This was the dilemma faced by scientists researching ...
Feb 16, 2016
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Radiotherapy is a crucial component in cancer treatment, used in 50 to 60 percent of patients with cancer. It is traditionally used for localized cancers—such as head and neck, cervical, prostate, lung and brain cancers—with ...
Jun 22, 2021
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Immunotherapy is a type of cancer treatment that uses the body's own immune system to fight tumor cells. While much focus has been on engaging T cells for fighting cancer, less attention has been given to directing the complement ...
Jun 29, 2023
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It doesn't often happen that army generals switch sides in the middle of a war, but when cancer's attack is underway, it may even cause a gene that acts as the body's master defender to change allegiance. As reported recently ...
Jul 25, 2018
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A new research perspective was published in Oncotarget, titled "Disruption of retinol-mediated IL-6 expression in colon cancer-associated fibroblasts: new perspectives on the role of vitamin A metabolism."
May 3, 2023
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