A new research perspective titled "HER3- A key survival pathway and an emerging therapeutic target in metastatic colorectal cancer and pancreatic ductal adenocarcinoma" has been published in Oncotarget.
May 24, 2023
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Immunotherapies have revolutionized cancer treatment, offering hope to those whose malignancies have stubbornly survived other existing treatments. Yet solid tumor cancers are often resistant to these approaches.
Feb 13, 2017
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Natural killer (NK) cells play a crucial role in the first line of host defense by eliminating bacteria, viruses, and mutated cells that might become cancer cells. While the interferon-gamma (IFN-γ ) typically plays a pivotal ...
May 30, 2024
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Northwestern Medicine investigators led by Amy Heimberger, MD, Ph.D., the Jean Malnati Miller Professor of Brain Tumor Research and vice chair for Research in the Department of Neurological Surgery, have discovered a new ...
Mar 21, 2024
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When foreign antigens trigger an immune response, T cells respond by proliferating and differentiating into two groups—effector and memory cells. Epigenetic and transcriptional pathways mediate this response, but the cells ...
Feb 28, 2024
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A scientist at the University of Virginia School of Medicine, working with local biotech company HemoShear Therapeutics, has created a physical, three-dimensional model of a cancer tumor that can replicate the complex nature ...
May 7, 2018
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An article published recently in Tumor Microenvironment and Therapy - an open access journal by Versita, defines a novel mechanism of tumor hypoxia induced by the longitudinal gradient of residual oxygen along tumor vessels ...
May 9, 2013
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A new research study at the Institute of Molecular Biology and Biotechnology (IMBB) of the Foundation for Research and Technology-Hellas (FORTH), published in the journal PNAS, reveals how cancer cell intrinsic mechanisms ...
Aug 10, 2023
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A recent study has discovered the function of mechanical constraints in glioblastoma. This study led by Prof. Chen from the Department of Biomedical Engineering at New York University explored the underlying mechanotransductive ...
Apr 2, 2024
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Radiotherapy (RT) is a primary method of tumor treatment. However, in clinical practice, radiotherapy still suffers from shortcomings such as serious side effects, limited efficacy, and tumor metastasis and recurrence due ...
Jan 10, 2023
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