Immunotherapies have revolutionized cancer treatment, offering hope to those whose malignancies have stubbornly survived other existing treatments. Yet solid tumor cancers are often resistant to these approaches.
Feb 13, 2017
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Massachusetts General Hospital investigators have found new evidence that the tumor necrosis factor receptor type II (TNFR2) may be a major target for immuno-oncology treatments, which induce a patient's immune system to ...
Jan 17, 2017
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The mechanical resistance of tumors and collateral damage of standard treatments often hinder efforts to defeat cancers. A team of researchers from CNRS, the French National Institute of Health and Medical Research (INSERM), ...
Jan 3, 2017
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An important parcel must be delivered to the correct place. It is so important that it can be a question of life or death. However, uneven streets and missing railings risk to bring it off the road and leave it undelivered. ...
Dec 12, 2016
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OHSU researcher Sudarshan Anand, Ph.D., has a contemporary analogy to describe microRNA: "I sometimes compare MicroRNA to tweets—they're short, transient and constantly changing."
Dec 2, 2016
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Understanding the effects of certain targeted therapies on antitumor immunity is necessary to design combined interventions for more effective cancer treatment. In the past, data have shown that trametinib, an FDA-approved ...
Nov 1, 2016
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While the role of estrogen signaling in tumor development is well understood in breast and ovarian cancer, its role in anti-tumor immunity has not been extensively studied. However, new research from The Wistar Institute ...
Oct 17, 2016
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Researchers at Bellvitge Biomedical Research Institute (IDIBELL) have published a study in Oncotarget that highlights the importance of the tumor environment as a source of resistance to treatment in colorectal cancer, the ...
Sep 6, 2016
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The microenvironment that supports a cancerous tumor also starves the immune cells that the body sends in to destroy the cancer, University of Pittsburgh Cancer Institute (UPCI) scientists revealed in a discovery that holds ...
Jul 29, 2016
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Researchers at Vanderbilt University Medical Center have discovered a potential way to "tune up" the immune system's ability to kill cancer cells.
May 16, 2016
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