Investigators at the Children's Center for Cancer and Blood Diseases at Children's Hospital Los Angeles have identified new findings about an immune cell - called a tumor-associated macrophage - that promotes cancer instead ...
Sep 21, 2017
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(HealthDay)—β2-adrenergic receptor (β-AR) signaling in host immune cells regulates CD8+ T-cell frequency and functional orientation within the tumor microenvironment, according to a study published online Aug. 17 in Cancer ...
Sep 13, 2017
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A novel mitochondrial variant of the protein Syntaphilin, or SNPH, which orchestrates the choice between cancer cell proliferation and metastasis in response to oxygen and nutrient shortage in the tumor microenvironment, ...
Sep 11, 2017
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T lymphocytes found in tumors and implicated in killing tumor cells cope with the shortage of oxygen and nutrients in the tumor microenvironment by using fat as the main source of energy. Promoting a switch from glucose to ...
Sep 11, 2017
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Whenever an organism is damaged, the cells surrounding the wound receive signals to proliferate more intensely to regenerate the injured tissue. The same thing happens with cancer—tumor cells may be all but eliminated by ...
Aug 28, 2017
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(HealthDay)—Telomere attrition occurs in tumor cells from patients with hepatocellular carcinoma (HCC), and shortened telomeres are independent prognosticators for HCC patients, according to a study published online Aug. ...
Aug 24, 2017
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It's a metabolite found in essentially all our cells that, like so many things, cancer overexpresses. Now scientists have shown that when they inhibit 20-HETE, it reduces both the size of a breast cancer tumor and its ability ...
Jul 12, 2017
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Brain tumors recruit immune cells derived from bone marrow to transform what began as benign masses into deadly malignancies, according to two studies from Weill Cornell Medicine scientists. The findings suggest that inhibiting ...
May 2, 2017
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It's not just what's inside breast cancer cells that matters. It's also the environment surrounding cancer cells that drives the disease, according to researchers at the University of North Carolina Lineberger Comprehensive ...
Mar 31, 2017
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Scientists at The Wistar Institute have shown that an anti-diabetic drug can inhibit the growth of melanoma in older patients by activating an anti-aging gene that in turn inhibits a protein involved in metastatic progression ...
Feb 23, 2017
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