Diseases, Conditions, Syndromes

New mitochondrial disease identified in identical twins

In a set of identical twins, investigators led by researchers at Massachusetts General Hospital (MGH) and Children's Hospital Philadelphia (CHOP) have identified a mitochondrial disease not previously reported.

Medical research

Mitochondria could boost immunotherapy effectiveness

Boosting mitochondrial function in a subpopulation of T cells could make cancer immunotherapy more effective, according to a recent study published in the Proceedings of the National Academy of Sciences (PNAS).

Neuroscience

Serotonin boosts neuronal powerplants protecting against stress

Mitochondria in neurons are the powerhouses that generate energy to execute cellular functions and regulate neuronal survival under conditions of stress. Collaborative research by Prof. Vidita Vaidya and Prof. Ullas Kolthur-Seetharam ...

Medical research

Researchers reformulate the model of mitochondrial function

The discovery confirms the model proposed by the team in 2008 to account for observations that could not be explained by the established model of mitochondrial function. Mitochondria are the organelles in the interior of ...

Diabetes

A link between type 2 diabetes and mitochondrial function

Type 2 diabetes is a chronic condition that is characterized by resistance to or insufficient production of insulin, a hormone that controls sugar movement into cells. In certain tissues, insulin resistance has been associated ...

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