Medical research

Study ties aging to oxidative damage in mitochondria

As long as humans have been alive, they've been seeking ways to extend life just a little longer. So far no one has found the fountain of youth, but researchers have begun to understand how humans age, little by little, offering ...

Alzheimer's disease & dementia

A new understanding of Alzheimer's

Although natural selection is often thought of as a force that determines the adaptation of replicating organisms to their environment, Harvard researchers have found that selection also occurs at the level of neurons, which ...

Genetics

Researchers uncover the genomics of health

Most diseases have a genetic component. To better understand disease, researchers led by the Garvan Institute of Medical Research are analysing genetic information to determine what keeps us healthy.

Genetics

Mitochondrial genome mutates when reprogrammed

Induced pluripotent stem cells (iPS cells) are truly talented multi-taskers. They can reproduce almost all cell types and thus offer great hope in the fight against diseases like Alzheimer's and Parkinson's. However, it would ...

Genetics

T cells require healthy mitochondria, research shows

All cells have their own power plants, called mitochondria. There are often more than 100 mitochondria per cell and each possesses their own genome, which in turn contains genes responsible for energy production. If errors ...

Genetics

New mutations accumulate in reproductive cells of older mice

Older mice have more new mutations—changes in DNA sequence that occur in the individual rather than being inherited from a parent—than younger mice in the genomes of their mitochondria, according to researchers at Penn ...

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