Genetics

How to analyze your genome; Part I—Mitochondrial DNA

Genome analysis today is basically blind. It typically proceeds by randomly inspecting a smattering of possible variants that are only loosely associated with some disease or physical trait. Unless you already have a major ...

Genetics

Mothers curse linked to male infertility

(Medical Xpress) -- Researchers have discovered the first real evidence of the 'mother's curse' and its connection to male infertility due to genetic mutations in mitochondria. Led by Dr. Damian Dowling from Monash University ...

Inflammatory disorders

DNA building blocks regulate inflammation

Mitochondria are the energy suppliers of our body cells. These tiny cell components have their own genetic material, which triggers an inflammatory response when released into the interior of the cell. The reasons for the ...

Genetics

What are mitochondria and how did we come to have them?

We've probably all heard of mitochondria, and we may even remember learning in school that they are the "powerhouses of the cell" – but what does that actually mean, and how did they evolve? To answer this question, we ...

Health

Eight ways chemical pollutants harm the body

A new review of existing evidence proposes eight hallmarks of environmental exposures that chart the biological pathways through which pollutants contribute to disease: oxidative stress and inflammation, genomic alterations ...

Genetics

T cells require healthy mitochondria, research shows

All cells have their own power plants, called mitochondria. There are often more than 100 mitochondria per cell and each possesses their own genome, which in turn contains genes responsible for energy production. If errors ...

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