Type 2 diabetes is a chronic condition that is characterized by resistance to or insufficient production of insulin, a hormone that controls sugar movement into cells. In certain tissues, insulin resistance has been associated ...
Oct 1, 2013
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Gender-specific differences between the levels and structures of proteins present in the white matter and the mitochondria of the brains of men and women suffering from dementia have been revealed for the first time in a ...
Mar 16, 2016
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The rhythm in a working heart is regulated by electrical impulses. Disturbances of this bioelectrical process can result in cardiac arrhythmias, or irregularities in heartbeat—a common ailment that can lead to illness and ...
Jul 13, 2021
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A lack of a particular mitochondrial protein in genetically manipulated mice has shown to trigger events in the body that causes mild heart hypertrophy (enlargement) and severe fatty liver disease.
Apr 21, 2015
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Patients with colon and rectal cancer have somatic insertions of mitochondrial DNA into the nuclear genomes of the cancer cells, University of Alabama at Birmingham researchers report in the journal Genome Medicine.
Apr 12, 2017
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No specific treatments are currently available for triple negative breast cancer (TNBC), a type of tumor that lacks the receptors targeted by many breast cancer therapies. Although many TNBC tumors lack two tumor suppressors, ...
Aug 29, 2016
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Charcot-Marie-Tooth disease is an inherited disorder that leads to a gradual loss of motor neurons and, eventually, paralysis. The condition is caused by genetic mutations that disrupts cells' energy factories, called mitochondria. ...
Oct 24, 2016
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(Medical Xpress)—Researchers at the Virginia Commonwealth University Parkinson's and Movement Disorders Center have found that mitochondrial quality and functional capacity play an important role in Parkinson's disease.
Mar 19, 2013
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In Leigh syndrome, infants are born apparently healthy only to develop movement and breathing disorders that worsen over time, often leading to death by the age of 3. The problem is that the mitochondria responsible for powering ...
Sep 6, 2011
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A research team led by Prof. Dr. Carola Hunte has succeeded in describing how the antimalarial drug atovaquone binds to its target protein. The scientists used x-ray crystallography to determine the three-dimensional structure ...
Jun 6, 2014
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