Diseases, Conditions, Syndromes

How Roquin controls the activity of immune cells

Ludwig Maximilians University Munich (LMU) immunologists have discovered how mutations in Roquin-1 trigger autoimmunity, but can also improve the body's fight against cancer cells.

Diabetes

Experimental compound counters diabetic complications

An experimental compound reduced complications of type 1 and type 2 diabetes in mice—not by lowering blood sugar—but by countering its consequences: cell death, inflammation, and organ damage.

Medications

Blocking hyperinflammatory response by repurposing a cancer drug

As we've seen during the COVID-19 pandemic, serious infections sometimes trigger an excessive inflammatory reaction that does as much harm—or more—than the infection itself. New research at Boston Children's Hospital ...

Immunology

How the immune system keeps the intestinal flora in balance

The bacteria living in the intestine consist of some 500 to 1000 different species. They make up what is known as the intestinal flora, which plays a key role in digestion and prevents infections. Unlike pathogens that invade ...

Diseases, Conditions, Syndromes

Managing inflammation through the endothelin system

Experts in the endothelin system are investigating how regulation of this system can serve to improve diseases of inflammation such as lupus. Endothelins are a class of peptides that play a role in regulating blood pressure. ...

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