Immunology

Changed established truth about the immune system

Protein in the blood did not have the function researchers believed in the interaction between two of the body's defense systems. Professor Tom Eirik Mollnes and colleagues thereby changed an established truth.

Oncology & Cancer

New discovery enhances understanding of colorectal cancer

MUSC Hollings Cancer Center researchers discovered a novel mechanism showing how a certain gene mutation can allow tumors to evade detection by the immune system in colorectal cancer patients. The study, which was published ...

Genetics

When mad AIOLOS drags IKAROS down: A novel pathogenic mechanism

Primary immunodeficiencies, such as severe combined immunodeficiency disease (SCID), occur when the immune system does not work properly, leading to increased susceptibility to various infections, autoimmunity, and cancers. ...

Oncology & Cancer

Looking at tumors through a new lens

Neoadjuvant immune checkpoint blockade (ICB) is a promising treatment for melanoma and other cancer types, and has recently been shown to provide a modest survival benefit for patients with recurrent glioblastoma. To improve ...

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