Psychology & Psychiatry
Study links stress to Crohn's disease flare-ups
A possible link between psychological stress and Crohn's disease flare-ups has been identified by a McMaster University-led study.
Nov 18, 2021
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Page 11 - News tagged with modeling system
Medications
Blocking hyperinflammatory response by repurposing a cancer drug
As we've seen during the COVID-19 pandemic, serious infections sometimes trigger an excessive inflammatory reaction that does as much harm—or more—than the infection itself. New research at Boston Children's Hospital ...
Nov 12, 2021
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Neuroscience
Alzheimer's disease may cause vicious circle between brain network and immune cell dysfunctions
Studying the complex causes of Alzheimer's disease, and how to treat and prevent this condition, is like solving a many-piece puzzle, with scientists each tackling a small section, unsure of how it might fit into the larger ...
Oct 26, 2021
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Immunology
How the immune system keeps the intestinal flora in balance
The bacteria living in the intestine consist of some 500 to 1000 different species. They make up what is known as the intestinal flora, which plays a key role in digestion and prevents infections. Unlike pathogens that invade ...
Oct 13, 2021
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Immunology
The immune system's double agents
A new Tel Aviv University study examined for the first time the development of a glioblastoma cancerous tumor in animal models with a normal immune system, in order to best simulate the development of the tumor in humans. ...
Oct 4, 2021
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Oncology & Cancer
Lab grown tumor models could improve treatment for pancreatic cancer
An international team of scientists have created a three-dimensional (3-D) pancreatic cancer tumour model in the laboratory, combining a bioengineered matrix and patient-derived cells that could be used to develop and test ...
Sep 24, 2021
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Medical research
Engineering CAR T cells to deliver endogenous RNA wakes solid tumors to respond to therapy
Chimeric antigen receptor (CAR) T cell therapy, which uses engineered T cells to treat certain types of cancers, has often been a challenging approach to treating solid tumors. CAR T cells need to recognize a specific target ...
Sep 2, 2021
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Genetics
When mad AIOLOS drags IKAROS down: A novel pathogenic mechanism
Primary immunodeficiencies, such as severe combined immunodeficiency disease (SCID), occur when the immune system does not work properly, leading to increased susceptibility to various infections, autoimmunity, and cancers. ...
Jul 16, 2021
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Oncology & Cancer
Potential drug target for difficult-to-treat breast cancer: RNA-binding proteins
In cancer research, it's a common goal to find something about cancer cells—some sort of molecule—that drives their ability to survive, and determine if that molecule could be inhibited with a drug, halting tumor growth. ...
Jul 2, 2021
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Oncology & Cancer
Looking at tumors through a new lens
Neoadjuvant immune checkpoint blockade (ICB) is a promising treatment for melanoma and other cancer types, and has recently been shown to provide a modest survival benefit for patients with recurrent glioblastoma. To improve ...
Jun 29, 2021
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